Rejuran Collagen Stimulation

Introducing Rejuran, the latest in Bio Skin Healing. Rejuran is a gel formulation containing Polynucleotide sourced from wild salmon DNA fragments, extracted through exclusive DOT™️ technology (DNA Optimising Technology). Unlike traditional skin collagen boosters, Rejuran harnesses the power of bio-active DNA molecules, stimulating skin regeneration and effectively repairing damage while mitigating undesirable inflammation.

What is involved in having Rejuran treatment?

Before any treatment can take place, a medical consultation with a doctor is required. During this consultation the doctor will assess the condition of the skin and prescribe an appropriate treatment, which may or may not include Rejuran. The consultation involves;

• A detailed medical history taken, including an assessment of your pre-consultation paperwork
• The skin is examined for skin laxity, volume loss, texture, and dynamic and static lines.
• Clinical photos and videos of the face are taken
• A VISIA Skin Analysis scan is performed for an objective view on the skin’s condition
• A treatment plan, including costs, is provided
• The risks and benefits of any proposed treatment are explained
• A consent form is completed before the treatment commences.

Consultations for Rejuran are available with our doctors at our Lower Templestowe, Berwick and Beaumaris clinics.

What is Rejuran treatment?

Rejuran is the brand name for a treatment that contains Polynucleotides, which are DNA fragments derived from salmon. These Polynucleotides promote skin regeneration, improve elasticity, and reduce the appearance of fine lines and wrinkles when injected into the skin. Rejuran injections are often used as part of anti-ageing and skin rejuvenation procedures, especially for additional collagen stimulation in the upper layers of the skin.

Launched in Korea in 2014, Rejuran was exclusively used in Asian countries such as Korea and Singapore, before being approved in Australia in July 2023.

What is in Rejuran?

Rejuran is an injectable product containing Polynucleotides from wild salmon, otherwise known as Sodium DNA. These polynucleotides are short DNA fragments, typically sourced from salmon DNA or other marine organisms. When injected into the skin, they are believed to offer several benefits for skin health and appearance.

Rejuran is placed into the dermis layer of the skin using a method known as mesotherapy to stimulate the fibroblasts to produce collagen.

Is Rejuran the same as other wrinkle treatments?

Rejuran is an injectable Polynucleotide which stimulates collagen production in the skin. It is very different from products which provide volume and fullness.

Unlike treatments that focus on providing volume, Rejuran’s Polynucleotide is specifically formulated to target the stimulation of collagen within the superficial or upper layers of the skin. Rejuran aims to promote natural collagen production, which decreases with ageing, to address visible signs of ageing.

Where can Rejuran injections be used?

There are several different formulations of Rejuran available. We use both Rejuran and Rejuran I.

Rather than targeting specific areas such as cheeks, temples or the forehead, Rejuran is used as a full face treatment. Rejuran can also be used to treat the skin on the neck area.

Rejuran I is specifically formulated to be used around the under eye area, promoting collagen and addressing fine lines and signs of skin ageing.

What does Rejuran treatment involve?

Patients are requested to arrive at their appointment free of makeup, moisturiser and sunscreen. Upon arrival, patients are prepared for treatment by having pre-treatment photographs taken and a VISIA skin scan is performed to measure the skin’s health and condition. An anaesthetic cream is then applied to the treatment area.

Rejuran is administered by the practitioner to the treatment area within the upper layers of the skin.

Once the treatment has been completed, we request that patients book a follow-up appointment in 2 to 4 weeks for further photographs and review.

What are the risks and side effects of Rejuran injections?

Rejuran, like all medical procedures, come with potential risks and side effects. It’s essential to be aware of these considerations before commencing the treatment. Here’s an overview of the associated risks and side effects, as well as guidelines on what to avoid after Rejuran treatment.

The risks and side effects associated with Rejuran treatment include:

• Lumps or bumps: In most cases, patients develop lumps or bumps under the skin at the injection sites, which may look similar to mosquito bites. These usually subside within 24 hours.
• Bruising and swelling:  Mild swelling is common, typically resolving within a few days. Whilst we take precautions to avoid bruising, such as using the Accuvein to visualise veins to avoid bruising, it may still occur. If bruising occurs, it typically subsides within a few days.
• Infection: While rare, there is a minimal risk of infection at the injection sites. Following proper aftercare instructions, refraining from using skin care for 24 hours following treatment, and not touching the treated area can help mitigate this risk.
• Allergic reactions: Although uncommon, allergic reactions to components of Rejuran can occur. It’s crucial to inform the practitioner of any known allergies beforehand.
• Discomfort: Mild discomfort during or after the treatment is possible. It’s advisable to communicate any persistent, severe or escalating pain to your practitioner.

What to avoid after Rejuran

• Excessive sun exposure: Protect the treated areas from prolonged sun exposure to reduce the risk of pigmentation changes. Use sunscreen with high SPF.
• Intense physical activity: Avoid strenuous exercise or activities that may increase blood flow to the treated areas immediately after the procedure.
• Harsh skin care products: Refrain from using harsh or abrasive skin care products on the treated skin, and follow the recommended post-treatment skin care routine provided by your practitioner.

FAQs

Are Rejuran injections painful?

Topical anaesthetic cream is applied before treatment to numb the area to be treated. Following treatment, temporary discomfort around the injection sites may occur as the anaesthetic cream wears off.

How long do the results last?

Due to the natural ageing process, Rejuran results are not permanent. Results can vary from person to person, and factors such as individual skin characteristics, lifestyle, and the specific concerns being addressed can influence the longevity of the effects.

The collagen stimulation initiated by Rejuran tends to have a gradual and cumulative effect, with results becoming noticeable after a series of sessions.

Depending on the patient’s age, skin quality, and general health, a course of 3 treatments 2 to 3 weeks apart may be recommended. This is followed by a treatment every 6-12 months to maintain skin condition through continued collagen stimulation.

Can I combine Rejuran injections with other treatments?

Yes, Rejuran injections can be combined with other treatments, and the decision to do so depends on an individual’s specific goals and the advice of their practitioner. Combining treatments can offer comprehensive and synergistic benefits. Here are some common combinations:

• Wrinkle-reducing treatments: Combining Rejuran with various types of wrinkle-reducing treatments is a common approach. While Rejuran works on skin texture and collagen, wrinkle-reducing treatments can target dynamic and static wrinkles.
• Chemical peels: Chemical peels can enhance the skin exfoliation process to exfoliate the upper most layers of the skin. This treatment combination should be performed a few weeks apart and can be used for addressing uneven skin tone and texture.
• Tixel: Tixel uses heat to create micro-injuries, stimulating collagen, while Rejuran provides additional support for collagen production and skin rejuvenation during the skin’s healing process.
• IPL treatment: Intense pulsed light (IPL), may be combined with Rejuran to address specific skin conditions such as pigmentation irregularities and sun damage.

How much do Rejuran injections cost?

Rejuran is priced on how many syringes a person needs, which can only be determined in a medical consultation. During the initial consultation, the doctor will assess the skin’s current condition and provide a detailed quotation.

Is Rejuran the same as wrinkle-reducing treatments?

Rejuran and wrinkle-reducing treatments are two very different treatments. Rejuran stimulates fibroblasts to produce collagen to improve skin texture, reduce fine lines, and rejuvenate the skin.

Wrinkle reducing treatments do not stimulate collagen, instead they work to reduce dynamic lines.

How many Rejuran treatments will I need?

The number of Rejuran treatments needed can vary based on individual factors such as the specific skin concerns being addressed and the current health condition of the skin. Generally, Rejuran treatments are performed in a series of 3 sessions, spaced 2 to 3 weeks apart.

How long until I see results from Rejuran?

Generally, it is common for individuals to notice gradual improvements in skin texture and firmness after the first few weeks following Rejuran treatments. However, for longevity of results, it is recommended that you complete the prescribed series of sessions and adhere to any post-treatment care instructions provided by your healthcare professional.

What is the downtime for Rejuran treatment?

The downtime for Rejuran treatment can vary among individuals, but many can resume their normal activities shortly after the procedure.

Due to the micro-injection points from the mesotherapy, there may be some redness and visible bumps. These usually subside within 24 to 48 hours.

Although rare, there may be some bruising due the puncturing of the skin.

However, the duration of downtime can vary among individuals, and it is influenced by factors such as individual skin sensitivity, the specific technique used, and any additional treatments performed simultaneously.

Last updated July 2024